TissuGlu® frees abdominoplasty patients
from postsurgical drains

Drains are the #1 complaint after surgery--in fact, 100% of patients who had drains would have
preferred not to in a recent survey.1


TissuGlu provides board-certified plastic surgeons with the opportunity to eliminate drains in abdominoplasty. TissuGlu delivers the strength and safety you need to manage fluid without drains, leading to a smoother, more desirable recovery and improving patient satisfaction.

As drains are such a major obstacle for many patients considering abdominoplasty, TissuGlu can help overcome objections and turn more consultations into surgical commitments.

The end result is a thriving practice with a base of loyal, satisfied patients who can help you grow through referrals.

abdomen and tissuglu gun

TissuGlu is the first and only FDA-approved synthetic surgical adhesive for internal use specifically designed with the strength to hold tissue layers together, reducing dead space after abdominoplasty. It creates a strong bond, maintaining tissue-to-tissue contact during healing, and breaks down into benign components readily metabolized by the body.

10 times stronger image

TissuGlu gives you the strength to help leave drains behind

TissuGlu is more than 10X stronger than fibrin sealant, which means you may be able to offer your patients a drain-free experience that allows them to recover more comfortably and return to daily activities more easily. Because TissuGlu has multiple points of contact, it is strong enough to resist shearing forces of the tissue. Each drop of adhesive can resist approximately 10 pounds of shear force.1

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Reference: 1. Data on file, Cohera Medical, Inc.

Important TissuGlu® Surgical Adhesive Safety Information


TissuGlu® Surgical Adhesive is indicated for the approximation of tissue layers where subcutaneous dead space exists between the tissue planes in abdominoplasty.


Do not use in patients with known or suspected allergies to urethane-based or isocyanate-containing products.


  • Do not use TissuGlu® Surgical Adhesive in patients who have had prior exposure to TissuGlu®. Immunological response associated with repeat TissuGlu® exposure has not been studied.
  • The effectiveness for the treatment of patients with BMI > 28 has not been established. Higher BMI patients have a propensity for fluid accumulation and may have an increased risk of seroma formation.
  • Effectiveness was not observed in weight loss patients undergoing abdominoplasty. Weight loss patients have a propensity for fluid accumulation and may have an increased risk of seroma formation and aspiration.

TissuGlu® may reduce the need for drains after surgery. By using TissuGlu® instead of drains, you may:

  • Return to normal activities more quickly
  • Experience less discomfort and pain than when drains are used
  • Have fewer invasive treatments for fluid management. The results showed that 73% of TissuGlu® patients had no treatments after surgery. However, some patients did require additional invasive treatments including reinsertion of drains.

Clinical studies were performed using TissuGlu®. There were no increased safety risks with the use of TissuGlu® than when drains were used. Potential complications associated with the use of the device and the tummy tuck procedures include seroma (fluid) formation. These complications may require treatments such as drain placement and/or fluid removal by needle, which may be performed in the operating room. Additional potential complications include wound healing issues, rash/redness, surgical site or incision infection, scarring, hematoma (bruise or swelling), incision separation, and immunological reaction.

Safety Information:
For full safety information please visit http://tissuglu.com/safety, contact your doctor, or call Cohera Customer Support at 1-800-641-7458.

TissuGlu® Surgical Adhesive is currently approved for sale in the United States for the approximation of tissue layers where subcutaneous dead space exists between the tissue planes in abdominoplasty. TissuGlu® Surgical Adhesive received European CE Mark in 2011, where it is approved for large flap surgical procedures such as abdominoplasty. TissuGlu® Surgical Adhesive is not approved for sale in any other region. Any questions related to the indication for use should be directed to your Cohera Medical Account Manager or to Cohera Medical Corporate Clinical Affairs. Refer to the complete TissuGlu® Surgical Adhesive Directions for Use for prescribing and usage information.